PhD Studentship in Pediatrics and Medical Genetics at Ghent University, 2011, Belgium

Our research team focuses on genetic and functional studies to identify and evaluate novel genes that are implicated in T-cell acute lymphoblastic leukemia (T-ALL). We have recently identified PHF6 as a novel tumor suppressor gene in T-ALL (Nature Genetics, 2010) and are currently evaluating its functional role. We also wish to evaluate the functional role of other, non-coding genes (miRNAs, lncRNAs) that might be implicated in T-ALL development. We therefore aim to develop a novel zebrafish model to study these T-ALL genes. In recent years, zebrafish have emerged as a potent model organism to study hematological diseases and can be easily modified genetically and used in large screens with compounds that might be of benefit in leukemia treatment.

-Knowledge/Experience Background: master in biomedical sciences/biotechnology/biochemistry/pharmaceutical sciences/medicine (MD); bio-engineer (cell and gene technology) or equivalent; high grades are certainly recommended; experience with in vivo models is a plus but not required – Skills Eager to learn and to work independently; strong communicative skills and a team-player (as the project will be interdisciplinary) -Attitudes Strongly motivated to perform scientific research; problem solving and critical attitude; personal interest in model organisms. Hoe solliciteren

Scholarship Deadline: 2011-07-15

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