The Jena School for Microbial Communication (JSMC) is funded by the German Excellence Initiative. JSMC is an ambitious Graduate School with over 150 PhD students who are educated in a structured, interdisciplinary training program based on top?level fundamental research. It conceptionally combines different research areas to a comprehensive picture of microbial communication. Institutes at five faculties of the Friedrich Schiller University Jena, six non?university research institutes as well as 12 partner companies are participating in this cutting?edge research and training program. The Ubiquitin?Proteasome?System (UPS) represents an important non?lysosomal cellular protein degradation machinery for the degradation of intracellular proteins to restore cell homeostasis. We will investigate the composition of the UPS in endothelial cells following infection with E. coli in vitro and in a mouse model. The BMBF funded Host Septomics Research Group is part of the Center for Innovation Competence “Septomics” at the Friedrich?Schiller?University of Jena. Our team analyzes the pathogen?host interactions with a strong focus on the host’s innate responses.
– a Master’s degree (or equivalent) in Natural or Life Sciences. Candidates about to earn their degree are welcome to apply. -required methodological or other skills: experiences in at best in infection mice models to study the pathogenesis of human infectious diseases, using state; art instruments and in vivo approaches will be a distinct advantage -high motivation and interest to join one of the interdisciplinary research areas of JSMC -creativity and interest to shape your own thesis project -an integrative and cooperative personality -very good communication skills in English (instruction language at JSMC)