The PhD position is associated with a NFR-funded project entitled “Injury and repair of mitochondrial DNA in myocardial ischemia”. The main targets of the project are to determine if mitochondrial DNA fragments act as endogenous danger signals released from the heart with sterile inflammation, how the downstream signaling occurs, and in which way they influence cell function. Mitochondrial DNA appears to signal through toll-like receptors. Signaling through other families of pattern recognition receptors may also be of interest to explore. Further, the nuclei encodes for genes involved in repairing mitochondrial DNA when it is injured.
•Applicants must hold a degree equivalent to a Norwegian Master degree •An interest in science •Good command of the English language